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Neurodegenerative disorders – Memory Research
Please check out our Therapeutic Focus for more details.
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Looking for collaborative partnerships for drug discovery and development efforts.
Venom peptide drug lead discovery
Drug lead optimization
Structure-activity relationship studies
Medicinal Chemistry expertise
Pharmacology, Stability, Structure Determination
Please contact A/Prof Markus Muttenthaler directly.
URGENT POSITIONS FOR STUDENTS IN:
Minium 3 days per week for 3 months. Contact with grades & CV
Honours/ Master Students:
Contact with grades & CV
PhD Students for University of Queensland and University of Vienna:
Apply at least 8 months prior to starting. Must acquire a daily scholarship, good grades are absolute necessary.
Sebaticals, Academic visitors and PhD visiting:
UQ Summer or Winter Research Project Description
Please use this template to create a description of each research project, eligibility requirements and expected deliverables. Project details can then be uploaded to each faculty, school, institute, and centre webpage prior to the launch of the program.
Molecular probe development to investigate the mechanisms of action of the trefoil peptides
November – February – Summer Research Project
Trefoil factor (TFF) peptides are key players in gastrointestinal epithelium protection by stabilizing the mucosal barrier and promoting wound healing. Many studies have highlighted their therapeutic potential for gastrointestinal disorders and their gut stability makes them interesting leads for drug design. Nonetheless, the mechanisms of action of the TFF peptides are not fully understood, hampering further development.
This project will be involved in the development of a set of advanced molecular probes that will enable to investigate the mechanism of action of this trefoil family by confocal microscopy and proteomics.
Expected outcomes and deliverables:
Applicants will gain skills in high performance liquid chromatography (HPLC), mass spectrometry, bioassays and peptide chemistry.
This project is open to applications from students with a background in chemistry or biochemistry.
Dr Markus Muttenthaler
Please contact firstname.lastname@example.org if interested.